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lipoate biosynthesis and incorporation IV (yeast)

State Icon Reaction EC-Number Confidence maximal confidence score from EnzymeDetector
S-adenosyl-L-methionine + [glycine-cleavage_complex_H_protein]_N6-octanoyl-L-lysine + sulfurated_[sulfur_carrier] + [2Fe-2S]-center <=> [glycine-cleavage_complex_H_protein]_N6-[(R)-lipoyl]-L-lysine + L-methionine + 5''-deoxyadenosine + unsulfurated_[sulfur_carrier] + [2Fe-2S]-center 2.8.1.8 lipoyl synthase

octanoyl-CoA + [pyruvate_dehydrogenase_E2_lipoyl-carrier_protein]-L-lysine <=> [pyruvate_dehydrogenase_E2_protein]_N6-octanoyl-L-lysine + CoA + H+ 2.3.1

S-adenosyl-L-methionine + [2-oxoglutarate-dehydrogenase_E2_protein]_N6-octanoyl-L-lysine + sulfurated_[sulfur_carrier] + [2Fe-2S]-center <=> [2-oxoglutarate_dehydrogenase_E2_protein]_N6-lipoyl-L-lysine + L-methionine + 5''-deoxyadenosine + unsulfurated_[sulfur_carrier] + [2Fe-2S]-center 2.8.1.8 lipoyl synthase

CoA + octanoyl-[acyl-carrier_protein] <=> [acyl-carrier_protein] + octanoyl-CoA 2.3.1
2.3.1.38 [acyl-carrier-protein] S-acetyltransferase
2.3.1.85 fatty-acid synthase system
2.8.3




S-adenosyl-L-methionine + [pyruvate_dehydrogenase_E2_protein]_N6-octanoyl-L-lysine + sulfurated_[sulfur_carrier] + [2Fe-2S]-center <=> [pyruvate_dehydrogenase_E2_protein]_N6-lipoyl-L-lysine + L-methionine + 5''-deoxyadenosine + unsulfurated_[sulfur_carrier] + [2Fe-2S]-center 2.8.1.8 lipoyl synthase

octanoyl-CoA + [2-oxoglutarate_dehydrogenase_E2_lipoyl-carrier_protein]-L-lysine <=> [2-oxoglutarate-dehydrogenase_E2_protein]_N6-octanoyl-L-lysine + CoA + H+ 2.3.1

octanoyl-[acyl-carrier_protein] + [glycine_cleavage_system_lipoyl-carrier_protein]-L-lysine <=> [glycine-cleavage_complex_H_protein]_N6-octanoyl-L-lysine + [acyl-carrier_protein] + H+ 2.3.1.181 lipoyl(octanoyl) transferase

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